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It induces the formation of micronuclei that contains the whole chromosomes or chromatids, it also induces the formation of micronuclei containing acentric chromosomal fragments, and that indicates its clastogenic ability, and finally, Patulin has both aneuploidogenic and clastogenic properties that could contribute to the carcinogenicity of this mycotoxin in the long-term studies which in turn could be hypothesized in humans as well (181)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 194.Scarmeas N., Stern Y., Mayeux R., Manly J.J., Schupf N., Luchsinger J.A